methyl (S)-(-)-4-chloro-3-hydroxybutanoate

methyl (S)-(-)-4-chloro-3-hydroxybutanoate - Names and Identifiers

Name	methyl (3S)-4-chloro-3-hydroxybutanoate
Synonyms	Methyl(S)-4-Chloro-3-Hydroxybutyrate (S)-Methyl-4-cloro-3-hydroxybutyrate Methyl (s)-4-chloro-3-hydroxybutyrate METHYL (S)-4-CHLORO-3-HYDROXYBUTYRATE (S)-METHYL 4-CHLORO-3-HYDROXYBUTYRATE methyl (3S)-4-chloro-3-hydroxybutanoate Methyl (3S)-4-chloro-3-hydroxybutanoate methyl (S)-(-)-4-chloro-3-hydroxybutanoate butanoic acid, 4-chloro-3-hydroxy-, methyl ester, (3S)- Butanoic acid, 4-chloro-3-hydroxy-, Methyl ester, (3S)-
CAS	86728-93-0
EINECS	1806241-263-5
InChI	InChI=1/C5H9ClO3/c1-9-5(8)2-4(7)3-6/h4,7H,2-3H2,1H3/t4-/m0/s1

methyl (S)-(-)-4-chloro-3-hydroxybutanoate - Physico-chemical Properties

Molecular Formula	C5H9ClO3
Molar Mass	152.58
Density	1.232±0.06 g/cm3(Predicted)
Boling Point	248.6±20.0 °C(Predicted)
Flash Point	104.2°C
Vapor Presure	0.00387mmHg at 25°C
pKa	12.73±0.20(Predicted)
Storage Condition	2-8℃
Refractive Index	1.45

methyl (S)-(-)-4-chloro-3-hydroxybutanoate - Introduction

methyl (3S)-is an organic compound with the formula C5H9ClO3. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: methyl (3S)-Colorless liquid.
-Solubility: Soluble in organic solvents, such as alcohols and ethers, insoluble in water.
-Melting point and boiling point: The melting point is about -20°C, and the boiling point is about 183°C.
-Structure: The molecule contains a chlorine atom and a hydroxyl group, as well as a methyl ester group and a butyric acid group.

Use:
- methyl (3S)-is often used in organic synthesis reactions as an important intermediate.
-It is often used in drug synthesis, especially the synthesis of therapeutically active compounds.
-In addition, it can also be used in the production of pesticides and cosmetics.

Preparation Method:
- methyl (3S)-can be obtained by reacting 3-chloropropanol with methyl carbonate.
-The reaction is generally carried out under an inert atmosphere, and methyl carbonate is generally slowly added dropwise at a low temperature (-10 to 0°C). After the reaction is completed, the product is filtered.

Safety Information:
- methyl (3S)-is a flammable liquid and should be kept away from open flames and high temperatures.
-Wear appropriate protective equipment such as chemical goggles, protective gloves and protective clothing during operation.
-avoid direct contact with the skin and inhalation of its vapor, such as inadvertent contact, should immediately rinse with plenty of water, and medical treatment.
-Store it in a closed container and place it in a cool, dry and well-ventilated place.

Last Update：2024-04-09 02:00:48